GSO ISO 21427-2:2013

ISO 21427-2:2006
Gulf Standard   Current Edition · Approved on 01 April 2013

Water quality -- Evaluation of genotoxicity by measurement of the induction of micronuclei -- Part 2: Mixed population method using the cell line V79

GSO ISO 21427-2:2013 Files

English 20 Pages
Current Edition Reference Language

GSO ISO 21427-2:2013 Scope

This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation

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